R# 4.0 EAP is the best thing that we can have right now, but you’ve got to be really careful about it. Especially, if you have habit of keeping your Visual Studio instances running for days, like I do.
Just today my R# finally ate all free space on his hard drive with logs (7 GBs) then threw an exception in all 3 VS 2008 instances. As if it was not enough, all VS instances crashed after that.

I guess that why it comes with a GIANT disclaimer that it is an early beta version ;)
However, I have seen similar stuff happening with it with regard to it eating memory.
Hm, in my case R# does not eat too much memory.
I.e. in large solution with 20+ projects and quite a number of referenced libraries it gets to 170-180Mb and stays there.